Description

Appearance

white powder, insipid, innocent

Qualify

Assay

≥98％

99.6%

Degree of Substitution

11.2-13.3

13.0

Molar of substitution

1.6-1.9

1.8

Loss on Drying

≤5.0％

3.9%

Optical density of a 10%solution (220-350nm)

≤1.0

Qualify

Optical density of a 10%solution (350-600nm)

≤0.1

Qualify

Chloride

≤0.2％

≤0.05％

Unsubstituted cyclodextrin

≤0.3％

Absent

Residue on Ignition

≤0.5％

0.39%

Heavy Metal (as pd)

≤0.0001%

＜0.0001%

Arsenic salt (AS)

≤0.0005%

＜0.0005%

Specific rotation

154-165º

156.2º

Solubility in water(25℃)

>750g/L

Qualify

TAMC(cfu/g)

≤1000

10

TYMC(cfu/g)

≤100

10

Salmonella/E. Coli (cfu/g)

Absent

Absent

Storage: at room temperature, in tightly closed container.

Characteristics and applications：

Methylated-β-cyclodextrin (Me-β-CD) is one of cyclodextrin derivatives that were widely used in modern researches and applications.

Me-β-CD can be soluble both in water and in organic solvents. In pharmaceuticals industry, it can increase solubility and bioavailability of drugs, so that the efficacy of drugs can last longer with less ingestion. It can adjust and control the drug release rate, reduce drug side-effects, and enhance the stability of drugs particularly for oil-soluble molecules.

In commodity chemicals and cosmetics, Me-β-CD can reduce microbial contamination and skin irritations, keep skin moist, mask bad odors, promote transdermal absorption of activeingredients.

Me-β-CD has a larger surface tension in common cyclodextrin derivatives.

Shandong Binzhou Zhiyuan biological Technology Co., LTD (Zhiyuan Bio-tech) is a innovative enterprise that is professional in cyclodextrins and their applications. Supported by Shandong University, Zhiyuan Bio-tech has a cyclodextrins research center that located in Jinan.

We have a strong research and development strength of the technical team which hasclose cooperation with Shandong University, Chinese Academy of Science and other world class research institutes. Now we can produce hydroxypropyl cyclodextrin, sulfobutyl ether-beta-cyclodextrin sodium salt, methyl cyclodextrin, mercapto cyclodextrin, amino cyclodextrin, ethanediamine cyclodextrin, piroxicam cyclodextrin, cyclodextrin polymers and other cyclodextrin derivtives. We can also synthesis custom designed cyclodextrin derivatives for your requirements.

Now we have Ion chromatograph (IC), Capillary electrophoresis (CE), High performance liquid chromatograph (HPLC), Gas chromatograph (GC), Fourier transform infrared spectroscopy (FTIR) and other imported advanced testing equipments. Multiple means of analysis and inspection help us ensure production quality and accelerate new production developing.

We are proud of our R&D team that are formed by domestic and overseas experts in the field of cyclodextrin. We believe we can provide first-class products and services for the partners in pharmaceutics, food, cosmetics, pesticides and new materials industries.