QUICK DETAILS:

Product Name	Eugenol	synonyms	4-Allyl-2-methoxyphenol
CAS No	97-53-0	MF	C10H12O2
Assay	98%	MW	164.20 g/mol
Appearance	Colorless or pale yellow liquid	Function	Eugenol is used in perfumeries, flavorings,essential oils and in medicine as a localantiseptic and anaesthetic

DESCRIPTION:

Eugenol is a phenylpropene, an allyl chain-substituted guaiacol. Eugenol is a member of the phenylpropanoids class of chemical compounds. It is a colorless to pale yellow oily liquid extracted from certain

essential oils especially from clove oil, nutmeg, cinnamon,basil and bay leaf. It is present in concentrations of 80–90% in clove bud oil and at 82–88% in clove leaf oil.

1. Antibacterial, lowering blood pressure. The Eugene have strong bactericidal, can be used as a

local analgesic dental caries, and both local antiseptic effect.

2. Can be used in the perfume fragrance as well as a variety of cosmetics fragrance and soap

flavor formula can also be used for food flavor deployment. Eugene has the rich carnation musk

odor, health and they enjoy the Department of flavor blending foundation, makeup, soap,

edible flavors blending both

Uses

★Eugenol is used in perfumeries, flavorings, essential oils and in medicine as a localantiseptic

and anaesthetic.Eugenol can be combined with zinc oxide to form a material-

known as zinc oxide eugenol – which has restorative and prosthodontic

applications indentistry. For example, zinc oxide eugenol is used for root canal sealing

★It can be used to reduce the presence of Listeria monocytogenes and Lactobacillus sakei

in food.

★They are also used in manufacturing stabilizers and antioxidants for plastics and rubbers. Attempts have been made to develop eugenol derivatives for intravenous injection,

such as propanididand.

The latter produced unacceptable side effects around the site of injection in many patients.

★It is one of many compounds that is attractive to males of various species of orchid bees, which apparently gather the chemical to synthesize pheromones; it is commonly

used as bait to attract and collect these bees for study.

★ It also attracts femal

cucumber beetle. It is recently discovered that eugenol and isoeugenol, floral volatile scent

compounds, are catalyzed by single type of enzyme in Gymnadenia species and gene

encoding for this enzyme is first functionally characterized gene in this species so far.

★It is commonly used in wisdom tooth extraction surgeries complicated by dry socket. Clove oil is growing in popularity as an anaesthetic for use on aquarium fish as well

as on wild fish when sampled for research and management purposes.Where readily available,

it presents a humane method to euthanise sick and diseased fish either by direct overdose or

to induce sleep before an overdose of ethanol.

★ It is also used in some mousetraps and kills certain human colon cancer cell lines in vitro

and in vivo.

★ Eugenol may have potential therapeutic effects against diseases characterized by excessive

osteoclast activity.

Side Effects

Toxicity

Eugenol is hepatotoxic, meaning it may cause damage to the liver. Overdose is possible,

causing a wide range of symptoms from blood in the patient's urine, to convulsions, diarrhoea,

nausea, unconsciousness, dizziness, or rapid heartbeat. According to a published 1993 report,

a two year old boy nearly died after taking between 5 and 10 ml.Eugenol is subject to restrictions

on its use in perfumery as some people may become sensitised to it, however, the degree to

which eugenol can cause an allergic reaction in humans is disputed.

Allergy

Eugenol is a component of Balsam of Peru, to which some people are allergic. When eugenol

is used in dental preparations such as surgical pastes, dental packing, and dental cement, it

may cause contact stomatitis and allergic cheilitis.The allergy can be discovered via a patch test.

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