Address:
Hunan,China
Main Products:
Plant extract,herbal extract,Organic Herb,Natural Colors,Herbal Medicine
Aralia chinensis Extract 98% Oleanolic acid Oleanol (UV-VIS)
oleanolic acid ursolic acid Olea europaea Extract
oleanolic acid Herb Source
Olea europaea L. Swertia mileensis T.N. Ho et W. L. Shi Ligustrum lucidum Ait
oleanolic acid Pharmacology
Protect liver and depress enzyme£¬ Anti-inflammation, Diuretic,Anti-cancer
Two triterpene acids, oleanolic acid (OA) and ursolic acid (UA), purified components from several Botanical drugs with known antitumor activity.
Ursolic acid (UA) and oleanolic acid (OA), isolated from Glechoma hederacea, inhibited Epstein-Barr virus activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in mouse skin. It is suggested that pretreatment of skin with UA may inhibit the first dramatic cellular event in tumor promotion caused by TPA1.
Ursolic acid and its isomer, oleanolic acid have been recommended for skin cancer therapy in Japan2. Topical cosmetic preparations containing ursolic acid/oleanolic acid have been patented in Japan for the prevention of topical skin cancer7. An ursolic acid/oleanolic acid ointment inhibited 7,12-dimethylbenz[a]anthracene (DMBA)-induced skin cancer in mice. Reportedly, 0% and 3% of mice developed cancer in 15 weeks and 30 weeks, respectively compared to 50% and 90% for the control mice7.
Ursolic acid treatment improves the health of skin and hair. Ursolic acid and its derivatives form oil-resistant barriers on the skin and hair as they do in the waxy coating of fruits3. Ursolic acid has been used to treat photoaged skin because it prevents and improves the appearance of wrinkles and age spots by restoring the skin¡¯s collagen bundle structures and its elasticity4. Concentrations of ursolic acid ranging from 0.01 to 50 mg have been reported for inclusion in skin treatment preparations5-6.